Blog
Understanding the Importance of Excipient Selection for Controlled Release
Controlled delivery formulations remain one of the favored tools for advancing the lifecycle of pharmaceutical products, and excipient selection is vitally important. A traditional strategy is to initially launch multiple daily doses of an immediate-release (IR)...
Combining In-Vivo Animal Models with Physiologically Based Pharmacokinetics (PBPK) Modeling to Optimize Oral Formulation Dosage Forms
Physiologically based pharmacokinetic modeling is well established in the pharmaceutical industry and is accepted by regulatory agencies for the prediction of drug–drug interactions. However, physiologically based pharmacokinetic modeling is valuable to address a much...
Novel Approaches for Enhancing the Oral Bioavailability & Absorption of Peptides
Oral Peptide Therapeutics - Technologies have been honed to overcome many of the challenges of administering peptide therapeutics orally, but obstacles remain before drug developers can fully realize the vast potential. Numerous technologies are currently in...
Nanoparticle formulation modalities: Light-scattering tools for screening and characterization
There are various light-scattering tools available to the pharma/biotech industry. One such company 'Wyatt Technology', provides macromolecular and nanoparticle characterization solutions recognised by the FDA and several related technologies to their product line...
Overcoming Drug Development Barriers for Peptide Products: Analytical, Physical and Formulation Aspects
The popularity of peptide therapeutics has increased significantly in recent years. Compared with chemical drugs, peptide drugs have little side-effects and little drug tolerance. Meanwhile, the specificity of treatment is high. Peptides are recognized for being...
Development and Regulation of Abuse Deterrent Opioid Medications
The opiod crisis has recently been taking up alot of coverage in the media in the US, Indeed, deaths from overdoses due to opiods in the US alone are greater than the deaths from auto accidents each year. Many organizations have been working diligently to develop...