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Structure-guided Discovery of Solid Forms to Drive Oral Bioavailability of Protease Inhibitors
Historically, oral administration has been considered the easiest and most convenient method of drug delivery, as it requires minimal expertise and invasiveness. Although oral delivery works fairly effectively for small-molecule drug products, oral delivery of...
Prodrug Approach for Improving Bioavailability
A prodrug is a medication or compound that metabolizes into a pharmacologically active drug after administration, offering opportunities to optimize the pharmaceutical property to improve bioavailability. Approximately 10% of all marketed drugs worldwide can be...
Applying Nanoparticle Delivery Approaches for Drug Development
Nanomedicines leading the way Nanotechnology offers multiple benefits in treating chronic diseases by site-specific, and target-oriented delivery of medicines. Nano-delivery systems utilized in drug development are very much still relatively new commercial approach....
In Situ Forming Injectable Hydrogel Formulations for Controlled Delivery of Peptides and Proteins
Given the rise of peptide and protein therapeutics in the pharmaceutical landscape, identifying the right delivery strategies that are patient-friendly and can be used over broad dose ranges has always been important considerations for the discovery and development of...
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