Nanomedicines leading the way
Nanotechnology offers multiple benefits in treating chronic diseases by site-specific, and target-oriented delivery of medicines. Nanodelivery systems utilized in drug development are very much still relatively new commercial approach. There are many opportunities and a few notable successes in targeted delivery of specific therapeutic agents in a controlled manner.
The continued development of nanomedicines has the potential to provide numerous benefits, including improved efficacy, bioavailability, dose–response, targeting ability, personalization, and safety compared to conventional medicines. There are a number of outstanding applications of the nanomedicines treating of various diseases but development still poses its own set of complex challenges.Approximately 40% of drugs on the market place and a high percentage of APIs in development are poorly soluble. Optimization of drug solubility and BA of therapeutics stands as one of the top challenges faced by the pharmaceutical and biotech industry today.
By way of followup, this week’s available deck is titled “Applying Nanoparticle Delivery Approaches” from Sharad Murdande at Pfizer. Sharad was a past speaker at our Global Drug Bioavailability Enhancement Summit. This presentation overviews methods for nanosuspension preparation / characterization, attrition wet milling process for extemporaneous preparation of nanocrystalline suspensions for phase I clinical studies, factors affecting nanosuspension preparation and properties of compounds used in nanocrystalline suspension formulation. It also examines investigation thermodynamic and kinetic properties of crystalline nanoparticles and nanocrystal solubility method development with a host of examples. To view this presentation and other novel delivery and bioavailability enhancement approaches, click below.
Our goal is to help you improve the performance of your drug products. Would you like to learn new strategies to improve patient compliance, bioavailability, stability and efficacy, all while reducing dosage, cost and decreasing time-to-market?
Join the drug development industry’s leading drug development specialists this March at the 2021 Global Drug Bioavailability Enhancement Summit in San Diego (March 3-4, 2021). Hear from 30+ senior drug bioavailability pioneers and network with 120+ senior drug development innovators and walk away with over 2 years of new drug formulation and bioavailability enhancement approaches strategies in just 2 days!
Planning to attend? Register early and save $800 or sending a group? Register 3 and the 4th is FREE. Sign-up and Gain Access to:
- 30+ industry-led speaker faculty over 2 full days sharing innovative drug development take-home strategies
- 12+ hours of networking sessions and breaks over two full days to learn from network with pharmaceutical and biotech senior formulation, development and delivery professionals
- 120+ senior participants spanning pharma, biotech and specialty delivery & technology companies
- Dynamic Tech Showcase Hall with multiple leading manufacturing, formulation development, delivery and modeling experts
Join over 1300 senior drug product development professionals in our free Novel Drug Discovery & Development Group. Members of this rapidly growing group will benefit by gaining access to an exclusive network of industry and academic professionals within the drug development arena. Members specialize in discovery, development, formulation, delivery and commercialization of innovative drug products.
Want to hear multiple weekly drug product development strategies and approaches from leading organizations and experts? Subscribe here and receive new podcast episodes, presentations, white papers, tips and resources directly from Curtis & Coulter weekly to your inbox