Jun 16, 2020 | Controlled Release, Drug Bioavailability, Main Blog, Peptide |
Improving the solubility of poorly soluble APIs remains one of the biggest challenges for pharmaceutical companies. Not to mention the lengthy and costly drug approval processes, generic incursion, rising development costs and the need for novel adherence strategies,...
Jun 15, 2020 | Controlled Release, Drug Bioavailability, Main Blog, Peptide |
Enhancing Drug Bioavailability and Solubility Approximately 40% of drugs on the market place and a high percentage of APIs in development are poorly soluble. Optimization of drug solubility and BA of therapeutics stands as one of the top challenges faced by the...
Jun 8, 2020 | Controlled Release, Drug Bioavailability, Main Blog, Peptide |
Extended Duration Parenteral Products as Patient Adherence Strategies For a number of years, extended-release parenteral formulations have garnered enormous attention due to their effective drug concentrations over extended periods and improve patient compliance...
May 26, 2020 | Controlled Release, Drug Bioavailability, Main Blog, Peptide |
Improving Adherence with Patient-Centric Formulations The term “patient centered,” “patient centric,” or “patient centricity” has increasingly grown in use in the scientific community in a wide variety of contexts. Generally, patient centric medicines are recognized...
Apr 15, 2020 | Controlled Release, Drug Bioavailability, Main Blog, Peptide |
Controlled delivery formulations remain one of the favored tools for advancing the lifecycle of pharmaceutical products, and excipient selection is vitally important. A traditional strategy is to initially launch multiple daily doses of an immediate-release (IR)...
Apr 14, 2020 | All Posts, Controlled Release, Drug Bioavailability, Main Blog |
Physiologically based pharmacokinetic modeling is well established in the pharmaceutical industry and is accepted by regulatory agencies for the prediction of drug–drug interactions. However, physiologically based pharmacokinetic modeling is valuable to address a much...
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